Heart Failure


The Practical Cardiology(TM) Heart Failure clinical resource center is an information hub for the latest in heart failure and heart failure management. With a focus on heart failure with reduced and preserved ejection fraction (HFrEF and HFpEF) this page features content including articles, videos, podcasts, and clinician-authored columns on FDA approvals, studies, guideline updates, and more.

Meta-Analysis Details Effects of SGLT2 Inhibitors in HFpEF

December 01, 2021

A systematic review and meta-analysis of phase 3 data on SGLT2 inhibitors in HFpEF suggest the class was associated with a 22% reduction in CV death and hospitalization but found no significant effect on CV death or all-cause mortality as individual end points.