Heart Failure


The Practical Cardiology(TM) Heart Failure clinical resource center is an information hub for the latest in heart failure and heart failure management. With a focus on heart failure with reduced and preserved ejection fraction (HFrEF and HFpEF) this page features content including articles, videos, podcasts, and clinician-authored columns on FDA approvals, studies, guideline updates, and more.

Medtronic Halts Sale of HVAD System, FDA Issues Warning to Stop New Implants

June 04, 2021

After receiving more than 100 complaints, including some involving death, Medtronic has halted sale of the HeartWare Ventricular Assist Device System and the FDA has issued a warning to clinicians to stop new implants of the device.

Analysis Details SGLT2 Inhibitors Benefit Across Heart Failure Subgroups

May 20, 2021

Hear from Deepak Bhatt, MD, MPH, on a systematic review and meta-analysis of SGLT2 inhibitor trials examining the effects of the class on heart failure across multiple subgroups, including those with preserved ejection fraction.

Increased EPA Levels Linked to Lower Heart Failure Risk in REDUCE-IT Trial

May 15, 2021

Data from post hoc analyses of REDUCE-IT indicate patients with increased on-treatment levels of EPA had a lower risk of heart failure and new hospitalization for heart failure when compared to their counterparts with the lowest on-treatment EPA levels.

Dapagliflozin (Farxiga) Receives Historic FDA Approval for Chronic Kidney Disease

April 30, 2021

The US FDA announced dapagliflozin (Farxiga) received approval for reducing the risk of kidney function decline, kidney failure, cardiovascular death, and hospitalization for heart failure in adults with chronic kidney disease who are at risk of disease progression in a statement on April 30.

Preterm Birth Associated with Increased Heart Failure Risk Throughout Adulthood

April 09, 2021

An analysis of nearly 4.2 million patients from a birth registry indicates being born preterm was linked to a significantly higher risk of developing heart failure during childhood and a 42% greater risk of heart failure in adulthood.