A prespecified analysis of the COMPLETE trial examined angina burden and QoL among patients in the study.
Both strategies were associated with improved angina-related QoL compared to baseline but results suggested a greater proportion of patients were free of angina in the complete revascularization group than in the CLO group at 3 years (84.3% vs 87.5%; ARD, 3.2% [95% CI, 0.7-5.7]; P=.013; NNT=13).
Dr. Deepak Bhatt provides further perspective in ACC.22 interview.
A multicenter randomized clinical trial, MOSAIC randomized patients to a home-based exercise program vs usual care for improving walking scores in those with peripheral artery disease.
Results suggested participation in a home-based walking program was associated with a 16.5-meter adjusted difference in 6-minute walking distance after 3 months compared to usual care, but investigators pointed out this failed to exceed the threshold for a large clinically important difference.
An NHLBI-funded analysis of the ARIC study sought to assess impact of obesity and age at menopause on heart failure risk among women.
Results of the 4500-person analysis indicate obesity was associated with increased risk of heart failure across all age groups, but this risk was most apparent among women with obesity who entered menopause at age of 55 years or later.